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Carnage invades an insane asylum looking to get some answers from some fellow crazy folk. Deadpool catches up to him here and thanks to the symbiotes that merged with him at the secret base he is able to separate Carnage and Shriek allowing him to fight them one at a time. Carnage begins to question his modus operandi. After incapacitating Deadpool he wanders off to think. Deadpool finds Shriek and makes sure she's no longer a problem. Carnage stumbles on her body and this turns out to be the final straw that causes him to stop his rampage and voluntarily incarcerate himself.
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